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APEH Inhibition Affects Osteosarcoma Cell Viability via Downregulation of the Proteasome

The proteasome is a multienzymatic complex that controls the half-life of the majority of intracellular proteins, including those involved in apoptosis and cell-cycle progression. Recently, proteasome inhibition has been shown to be an effective anticancer strategy, although its downregulation is of...

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Detalles Bibliográficos
Autores principales: Palumbo, Rosanna, Gogliettino, Marta, Cocca, Ennio, Iannitti, Roberta, Sandomenico, Annamaria, Ruvo, Menotti, Balestrieri, Marco, Rossi, Mosè, Palmieri, Gianna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5085647/
https://www.ncbi.nlm.nih.gov/pubmed/27669226
http://dx.doi.org/10.3390/ijms17101614