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Long-term consumption of an obesogenic high fat diet prior to ischemia-reperfusion mediates cardioprotection via Epac1-dependent signaling

BACKGROUND: Obesity is still considered a risk factor for cardiovascular disease, although more recent knowledge also suggests obesity to be associated with reduced morbidity and mortality - the “obesity paradox”. This study explores if long-term feeding of an obesogenic high fat diet renders the my...

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Detalles Bibliográficos
Autores principales: Edland, F., Wergeland, A., Kopperud, R., Åsrud, K. S., Hoivik, E. A., Witsø, S. L., Æsøy, R., Madsen, L., Kristiansen, K., Bakke, M., Døskeland, S. O., Jonassen, A. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127093/
https://www.ncbi.nlm.nih.gov/pubmed/27933093
http://dx.doi.org/10.1186/s12986-016-0147-1