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ΔNp63 mediates cellular survival and metastasis in canine osteosarcoma
p63 is a structural homolog within the 53 family encoding two isoforms, ΔNp63 and TAp63. The oncogenic activity of ΔNp63 has been demonstrated in multiple cancers, however the underlying mechanisms that contribute to tumorigenesis are poorly characterized. Osteosarcoma (OSA) is the most common prima...
Autores principales: | Cam, Maren, Gardner, Heather L., Roberts, Ryan D., Fenger, Joelle M., Guttridge, Denis C., London, Cheryl A., Cam, Hakan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5217036/ https://www.ncbi.nlm.nih.gov/pubmed/27391430 http://dx.doi.org/10.18632/oncotarget.10406 |
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