Molecular targeting of the Aurora-A/SMAD5 oncogenic axis restores chemosensitivity in human breast cancer cells

Although the majority of breast cancers initially respond to the cytotoxic effects of chemotherapeutic agents, most breast cancer patients experience tumor relapse and ultimately die because of drug resistance. Breast cancer cells undergoing epithelial to mesenchymal transition (EMT) acquire a CD44(...

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Detalles Bibliográficos
Autores principales: Opyrchal, Mateusz, Gil, Malgorzata, Salisbury, Jeffrey L., Goetz, Mathew P., Suman, Vera, Degnim, Amy, McCubrey, James, Haddad, Tufia, Iankov, Ianko, Kurokawa, Chenye B., Shumacher, Nicole, Ingle, James N., Galanis, Evanthia, D’Assoro, Antonino B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710966/
https://www.ncbi.nlm.nih.gov/pubmed/29207686
http://dx.doi.org/10.18632/oncotarget.20610

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710966/
https://www.ncbi.nlm.nih.gov/pubmed/29207686
http://dx.doi.org/10.18632/oncotarget.20610

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