Full and partial agonists evoke distinct structural changes in opening the muscle acetylcholine receptor channel

The muscle acetylcholine (ACh) receptor transduces a chemical into an electrical signal, but the efficiency of transduction, or efficacy, depends on the particular agonist. It is often presumed that full and partial agonists elicit the same structural changes after occupancy of their binding sites b...

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Detalles Bibliográficos
Autores principales: Mukhtasimova, Nuriya, Sine, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940249/
https://www.ncbi.nlm.nih.gov/pubmed/29680816
http://dx.doi.org/10.1085/jgp.201711881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5940249/
https://www.ncbi.nlm.nih.gov/pubmed/29680816
http://dx.doi.org/10.1085/jgp.201711881

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