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Spermidine: a physiological autophagy inducer acting as an anti-aging vitamin in humans?
Spermidine is a natural polyamine that stimulates cytoprotective macroautophagy/autophagy. External supplementation of spermidine extends lifespan and health span across species, including in yeast, nematodes, flies and mice. In humans, spermidine levels decline with aging, and a possible connection...
Autores principales: | Madeo, Frank, Bauer, Maria A., Carmona-Gutierrez, Didac, Kroemer, Guido |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6287690/ https://www.ncbi.nlm.nih.gov/pubmed/30306826 http://dx.doi.org/10.1080/15548627.2018.1530929 |
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