Interpretation of the mechanism of action of antituberculosis drug bedaquiline based on a novel two‐ion theory of energy coupling in ATP synthesis

Tuberculosis (TB) claims the lives of 1.3 million people each year, more than any other bacterial infection. Hence great interest was generated in health communities upon the recent introduction of the new diarylquinoline anti‐TB drug, bedaquiline. Bedaquiline acts by binding to the c‐subunit in the...

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Detalles Bibliográficos
Autor principal: Nath, Sunil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6336660/
https://www.ncbi.nlm.nih.gov/pubmed/30680327
http://dx.doi.org/10.1002/btm2.10106