Effects of intravenous oxycodone alone or in combination with naltrexone on measures of respiratory depression: a randomized placebo-controlled study

BACKGROUND: Abuse of prescription opioids, particularly by intravenous (IV) administration, can cause respiratory depression and death. ALO-02, an abuse-deterrent opioid formulation, is designed to release sequestered naltrexone upon manipulation by crushing, thereby antagonizing the pharmacologic e...

Descripción completa

Detalles Bibliográficos
Autores principales: Bass, Almasa, Webster, Lynn R., Matschke, Kyle T., Malhotra, Bimal K., Wolfram, Gernot
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360639/
https://www.ncbi.nlm.nih.gov/pubmed/30746121
http://dx.doi.org/10.1177/2042098618821274

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360639/
https://www.ncbi.nlm.nih.gov/pubmed/30746121
http://dx.doi.org/10.1177/2042098618821274

Ejemplares similares