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Dynamic inosinome profiles reveal novel patient stratification and gender-specific differences in glioblastoma
BACKGROUND: Adenosine-to-inosine (A-to-I) RNA editing is an essential post-transcriptional mechanism mediated by ADAR enzymes that have been recently associated with cancer. RESULTS: Here, we characterize the inosinome signature in normal brain and de novo glioblastoma (GBM) using new metrics that r...
Autores principales: | Silvestris, Domenico Alessandro, Picardi, Ernesto, Cesarini, Valeriana, Fosso, Bruno, Mangraviti, Nicolò, Massimi, Luca, Martini, Maurizio, Pesole, Graziano, Locatelli, Franco, Gallo, Angela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373152/ https://www.ncbi.nlm.nih.gov/pubmed/30760294 http://dx.doi.org/10.1186/s13059-019-1647-x |
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