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Modeling differentiation-state transitions linked to therapeutic escape in triple-negative breast cancer

Drug resistance in breast cancer cell populations has been shown to arise through phenotypic transition of cancer cells to a drug-tolerant state, for example through epithelial-to-mesenchymal transition or transition to a cancer stem cell state. However, many breast tumors are a heterogeneous mixtur...

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Detalles Bibliográficos
Autores principales:	Chapman, Margaret P., Risom, Tyler, Aswani, Anil J., Langer, Ellen M., Sears, Rosalie C., Tomlin, Claire J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6428348/ https://www.ncbi.nlm.nih.gov/pubmed/30856168 http://dx.doi.org/10.1371/journal.pcbi.1006840

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