Drug Solubility Enhancement through the Preparation of Multicomponent Organic Materials: Eutectics of Lovastatin with Carboxylic Acids

Lovastatin (LOV) is a drug used to treat hypercholesterolemia. Recent studies have identified its antioxidant effects and potential use in the treatment of some types of cancer. However, the low bioavailability related to its poor water solubility limits its use in solid oral dosage forms. Therefore...

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Detalles Bibliográficos
Autores principales: Araya-Sibaja, Andrea Mariela, Vega-Baudrit, José Roberto, Guillén-Girón, Teodolito, Navarro-Hoyos, Mirtha, Cuffini, Silvia Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470475/
https://www.ncbi.nlm.nih.gov/pubmed/30857331
http://dx.doi.org/10.3390/pharmaceutics11030112