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PG545 treatment reduces RRV-induced elevations of AST, ALT with secondary lymphoid organ alterations in C57BL/6 mice
Recently the anti-viral effects of prophylactic treatment with the low-molecular-weight heparan sulfate mimetic PG545 in Ross River virus (RRV) infected mice were reported. We further investigated the related, transient pathophysiology of PG545 drug treatment in RRV-infected and mock-infected PG545-...
Autores principales: | Supramaniam, Aroon, Bielefeldt-Ohmann, Helle, Rudd, Penny A., Webster, Julie, Ferro, Vito, Herrero, Lara J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553857/ https://www.ncbi.nlm.nih.gov/pubmed/31170255 http://dx.doi.org/10.1371/journal.pone.0217998 |
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