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A Free Radical Scavenger Ameliorates Teratogenic Activity of a DNA Hypomethylating Hematological Therapeutic
The spin-trap free radical scavenger N-tert-butyl-α-phenylnitron (PBN) ameliorated effects of several teratogens involving reactive oxygen species (ROS). We investigated for the first time whether PBN could ameliorate teratogenesis induced by a DNA hypomethylating hematological therapeutic 5-azacyti...
Autores principales: | Sobočan, Nikola, Katušić Bojanac, Ana, Sinčić, Nino, Himelreich-Perić, Marta, Krasić, Jure, Majić, Željka, Jurić-Lekić, Gordana, Šerman, Ljiljana, Vlahović, Maja, Ježek, Davor, Bulić-Jakuš, Floriana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Mary Ann Liebert, Inc., publishers
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6585171/ https://www.ncbi.nlm.nih.gov/pubmed/30672391 http://dx.doi.org/10.1089/scd.2018.0194 |
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