Cargando…

6β-Hydroxytestosterone, a metabolite of testosterone generated by CYP1B1, contributes to vascular changes in angiotensin II-induced hypertension in male mice

BACKGROUND: Previously, we showed that 6β-hydroxytestosterone (6β-OHT), a cytochrome P450 1B1 (CYP1B1)-derived metabolite of testosterone, contributes to angiotensin II (Ang II)-induced hypertension in male mice. This study was conducted to test the hypothesis that 6β-OHT contributes to increased va...

Descripción completa

Detalles Bibliográficos
Autores principales: Pingili, Ajeeth K., Jennings, Brett L., Mukherjee, Kamalika, Akroush, Wadah, Gonzalez, Frank J., Malik, Kafait U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6966856/
https://www.ncbi.nlm.nih.gov/pubmed/31948482
http://dx.doi.org/10.1186/s13293-019-0280-4