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iCa(2+) Flux, ROS and IL-10 Determines Cytotoxic, and Suppressor T Cell Functions in Chronic Human Viral Infections
Exhaustion of CD8(+) T cells and increased IL-10 production is well-known in chronic viral infections but mechanisms leading to loss of their cytotoxic capabilities and consequent exhaustion remain unclear. Exhausted CD8(+)T cells also called T suppressors are highly immune suppressive with altered...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068714/ https://www.ncbi.nlm.nih.gov/pubmed/32210950 http://dx.doi.org/10.3389/fimmu.2020.00083 |