Structure of the Neurotensin Receptor 1 in complex with β-arrestin 1

Arrestin proteins bind to active, phosphorylated G protein coupled receptors (GPCRs), thereby preventing G protein coupling, triggering receptor internalization, and affecting various downstream signaling pathways(1,2). While there exists a wealth of structural information delineating the interactio...

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Detalles Bibliográficos
Autores principales: Huang, Weijiao, Masureel, Matthieu, Qianhui, Qu, Janetzko, John, Inoue, Asuka, Kato, Hideaki E., Robertson, Michael J., Nguyen, Khanh C., Glenn, Jeffrey S., Skiniotis, Georgios, Kobilka, Brian K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7100716/
https://www.ncbi.nlm.nih.gov/pubmed/31945771
http://dx.doi.org/10.1038/s41586-020-1953-1