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Loss of ZC4H2 and RNF220 Inhibits Neural Stem Cell Proliferation and Promotes Neuronal Differentiation

The ubiquitin E3 ligase RNF220 and its co-factor ZC4H2 are required for multiple neural developmental processes through different targets, including spinal cord patterning and the development of the cerebellum and the locus coeruleus. Here, we explored the effects of loss of ZC4H2 and RNF220 on the...

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Detalles Bibliográficos
Autores principales: Zhang, Longlong, Ye, Maosen, Zhu, Liang, Cha, Jingmei, Li, Chaocui, Yao, Yong-Gang, Mao, Bingyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7408363/
https://www.ncbi.nlm.nih.gov/pubmed/32630355
http://dx.doi.org/10.3390/cells9071600