DNSN-1 recruits GINS for CMG helicase assembly during DNA replication initiation in C. elegans

Assembly of the CDC45-MCM-GINS helicase is the key regulated step during eukaryotic DNA replication initiation. Until now, it was unclear whether metazoa require additional factors not present in yeast. Here we show that Caenorhabditis elegans DNSN-1, the orthologue of human DONSON, functions during...

Descripción completa

Detalles Bibliográficos
Autores principales: Xia, Yisui, Sonneville, Remi, Jenkyn-Bedford, Michael, Ji, Liqin, Alabert, Constance, Hong, Ye, Yeeles, Joseph T.P., Labib, Karim P.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7615117/
https://www.ncbi.nlm.nih.gov/pubmed/37590372
http://dx.doi.org/10.1126/science.adi4932

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7615117/
https://www.ncbi.nlm.nih.gov/pubmed/37590372
http://dx.doi.org/10.1126/science.adi4932

Ejemplares similares