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Complexities of a protonatable substrate in measurements of Hoechst 33342 transport by multidrug transporter LmrP
Multidrug transporters can confer drug resistance on cells by extruding structurally unrelated compounds from the cellular interior. In transport assays, Hoechst 33342 (referred to as Hoechst) is a commonly used substrate, the fluorescence of which changes in the transport process. With three basic...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674423/ https://www.ncbi.nlm.nih.gov/pubmed/33208856 http://dx.doi.org/10.1038/s41598-020-76943-0 |