Role of IRE1α in podocyte proteostasis and mitochondrial health

Glomerular epithelial cell (GEC)/podocyte proteostasis is dysregulated in glomerular diseases. The unfolded protein response (UPR) is an adaptive pathway in the endoplasmic reticulum (ER) that upregulates proteostasis resources. This study characterizes mechanisms by which inositol requiring enzyme-...

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Detalles Bibliográficos
Autores principales: Navarro-Betancourt, José R., Papillon, Joan, Guillemette, Julie, Iwawaki, Takao, Chung, Chen-Fang, Cybulsky, Andrey V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677398/
https://www.ncbi.nlm.nih.gov/pubmed/33298866
http://dx.doi.org/10.1038/s41420-020-00361-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7677398/
https://www.ncbi.nlm.nih.gov/pubmed/33298866
http://dx.doi.org/10.1038/s41420-020-00361-4

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