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Sepsis is associated with mitochondrial DNA damage and a reduced mitochondrial mass in the kidney of patients with sepsis-AKI
BACKGROUND: Sepsis is a life-threatening condition accompanied by organ dysfunction subsequent to a dysregulated host response to infection. Up to 60% of patients with sepsis develop acute kidney injury (AKI), which is associated with a poor clinical outcome. The pathophysiology of sepsis-associated...
Autores principales: | van der Slikke, Elisabeth C., Star, Bastiaan S., van Meurs, Matijs, Henning, Robert H., Moser, Jill, Bouma, Hjalmar R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7831178/ https://www.ncbi.nlm.nih.gov/pubmed/33494815 http://dx.doi.org/10.1186/s13054-020-03424-1 |
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