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Small extracellular vesicles obtained from hypoxic mesenchymal stromal cells have unique characteristics that promote cerebral angiogenesis, brain remodeling and neurological recovery after focal cerebral ischemia in mice
Obtained from the right cell-type, mesenchymal stromal cell (MSC)-derived small extracellular vesicles (sEVs) promote stroke recovery. Within this process, microvascular remodeling plays a central role. Herein, we evaluated the effects of MSC-sEVs on the proliferation, migration, and tube formation...
Autores principales: | Gregorius, Jonas, Wang, Chen, Stambouli, Oumaima, Hussner, Tanja, Qi, Yachao, Tertel, Tobias, Börger, Verena, Mohamud Yusuf, Ayan, Hagemann, Nina, Yin, Dongpei, Dittrich, Robin, Mouloud, Yanis, Mairinger, Fabian D., Magraoui, Fouzi El, Popa-Wagner, Aurel, Kleinschnitz, Christoph, Doeppner, Thorsten R., Gunzer, Matthias, Meyer, Helmut E., Giebel, Bernd, Hermann, Dirk M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8187185/ https://www.ncbi.nlm.nih.gov/pubmed/34105014 http://dx.doi.org/10.1007/s00395-021-00881-9 |
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