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A nexus of miR-1271, PAX4 and ALK/RYK influences the cytoskeletal architectures in Alzheimer's Disease and Type 2 Diabetes

Alzheimer's Disease (AD) and Type 2 Diabetes (T2D) share a common hallmark of insulin resistance. Reportedly, two non-canonical Receptor Tyrosine Kinases (RTKs), ALK and RYK, both targets of the same micro RNA miR-1271, exhibit significant and consistent functional down-regulation in post-morte...

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Detalles Bibliográficos
Autores principales: Majumder, Piyali, Chanda, Kaushik, Das, Debajyoti, Singh, Brijesh Kumar, Chakrabarti, Partha, Jana, Nihar Ranjan, Mukhopadhyay, Debashis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8454712/
https://www.ncbi.nlm.nih.gov/pubmed/34409981
http://dx.doi.org/10.1042/BCJ20210175