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Evaluating Molecular Docking Software for Small Molecule Binding to G-Quadruplex DNA
G-quadruplexes are four-stranded nucleic acid secondary structures of biological significance and have emerged as an attractive drug target. The G4 formed in the MYC promoter (MycG4) is one of the most studied small-molecule targets, and a model system for parallel structures that are prevalent in p...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509811/ https://www.ncbi.nlm.nih.gov/pubmed/34639142 http://dx.doi.org/10.3390/ijms221910801 |