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Evaluating Molecular Docking Software for Small Molecule Binding to G-Quadruplex DNA

G-quadruplexes are four-stranded nucleic acid secondary structures of biological significance and have emerged as an attractive drug target. The G4 formed in the MYC promoter (MycG4) is one of the most studied small-molecule targets, and a model system for parallel structures that are prevalent in p...

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Detalles Bibliográficos
Autores principales: Dickerhoff, Jonathan, Warnecke, Kassandra R., Wang, Kaibo, Deng, Nanjie, Yang, Danzhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8509811/
https://www.ncbi.nlm.nih.gov/pubmed/34639142
http://dx.doi.org/10.3390/ijms221910801