Endogenous neurosteroids pregnanolone and pregnanolone sulfate potentiate presynaptic glutamate release through distinct mechanisms

BACKGROUND AND PURPOSE: Neurosteroids influence neuronal function and have multiple promising clinical applications. Direct modulation of postsynaptic neurotransmitter receptors by neurosteroids is well characterized, but presynaptic effects remain poorly understood. Here, we report presynaptic glut...

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Detalles Bibliográficos
Autores principales: Smejkalova, Tereza, Korinek, Miloslav, Krusek, Jan, Hrcka Krausova, Barbora, Candelas Serra, Miriam, Hajdukovic, Dragana, Kudova, Eva, Chodounska, Hana, Vyklicky, Ladislav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518729/
https://www.ncbi.nlm.nih.gov/pubmed/33988248
http://dx.doi.org/10.1111/bph.15529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8518729/
https://www.ncbi.nlm.nih.gov/pubmed/33988248
http://dx.doi.org/10.1111/bph.15529

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