IRF2 contributes to myocardial infarction via regulation of GSDMD induced pyroptosis

Interferon regulatory factor (IRF) 2 is a transcription factor belonging to the IRF family, which is essential for gasdermin D (GSDMD)-induced pyroptosis. Decreasing myocardial cell pyroptosis confers protection against heart damage and cardiac dysfunction caused by myocardial infarction (MI). The a...

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Detalles Bibliográficos
Autores principales: Li, Yongxing, Wang, Yan, Guo, Hua, Wu, Qinghua, Hu, Yamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8674697/
https://www.ncbi.nlm.nih.gov/pubmed/34878155
http://dx.doi.org/10.3892/mmr.2021.12556