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Persistence of Unintegrated HIV DNA Associates With Ongoing NK Cell Activation and CD34+DNAM-1brightCXCR4+ Precursor Turnover in Vertically Infected Patients Despite Successful Antiretroviral Treatment
The quantification of proviral DNA is raising interest in view of clinical management and functional HIV eradication. Measures of all unintegrated HIV DNA (uDNA) forms in infected reservoir cells provides information on recent replication events that is not found from other proviral DNA assays. To e...
Autores principales: | Taramasso, Lucia, Bozzano, Federica, Casabianca, Anna, Orlandi, Chiara, Bovis, Francesca, Mora, Sara, Giacomini, Mauro, Moretta, Lorenzo, Magnani, Mauro, Di Biagio, Antonio, De Maria, Andrea |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9088003/ https://www.ncbi.nlm.nih.gov/pubmed/35558085 http://dx.doi.org/10.3389/fimmu.2022.847816 |
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