A protocol to induce systemic autophagy and increase energy metabolism in mice using PEGylated arginine deiminase

Obesity is a prevalent metabolic disorder worldwide. Here, we describe a comprehensive protocol using pegylated arginine deiminase (ADI-EPG 20) to apply the concept that arginine depletion induces systemic autophagy to drive whole-body energy metabolism and weight loss in mice. We detail the steps f...

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Detalles Bibliográficos
Autores principales: Zhang, Yiming, DeBosch, Brian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249829/
https://www.ncbi.nlm.nih.gov/pubmed/35776644
http://dx.doi.org/10.1016/j.xpro.2022.101489

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9249829/
https://www.ncbi.nlm.nih.gov/pubmed/35776644
http://dx.doi.org/10.1016/j.xpro.2022.101489

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