Translation initiation site of mRNA is selected through dynamic interaction with the ribosome

Initiation of protein synthesis from the correct start codon of messenger RNA (mRNA) is crucial to translation fidelity. In bacteria, the start codon is usually preceded by a 4- to 6-mer adenosine/guanosine-rich Shine–Dalgarno (SD) sequence. Both the SD sequence and the start codon comprise the core...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Yi-Lan, Wen, Jin-Der
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295790/
https://www.ncbi.nlm.nih.gov/pubmed/35605125
http://dx.doi.org/10.1073/pnas.2118099119