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Nature vs. nurture: FOXP3, genetics, and tissue environment shape Treg function

The importance of regulatory T cells (Tregs) in preventing autoimmunity has been well established; however, the precise alterations in Treg function in autoimmune individuals and how underlying genetic associations impact the development and function of Tregs is still not well understood. Polygeneti...

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Detalles Bibliográficos
Autores principales: Raugh, Arielle, Allard, Denise, Bettini, Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9411801/
https://www.ncbi.nlm.nih.gov/pubmed/36032083
http://dx.doi.org/10.3389/fimmu.2022.911151