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Elevated Protein Kinase A Activity in Stomach Mesenchyme Disrupts Mesenchymal-epithelial Crosstalk and Induces Preneoplasia
BACKGROUND & AIMS: Mesenchymal-epithelial crosstalk (MEC) in the stomach is executed by pathways such as bone morphogenetic protein (BMP) and extracellular signal-regulated kinase (ERK). Mis-regulation of MEC disrupts gastric homeostasis and causes tumorigenesis. Protein Kinase A (PKA) crosstalk...
Autores principales: | Puri, Pawan, Grimmett, Garfield, Faraj, Rawah, Gibson, Laurielle, Gilbreath, Ebony, Yoder, Bradley K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9421585/ https://www.ncbi.nlm.nih.gov/pubmed/35690337 http://dx.doi.org/10.1016/j.jcmgh.2022.06.001 |
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