Neurocognitive trajectory and proteomic signature of inherited risk for Alzheimer’s disease

For Alzheimer’s disease–a leading cause of dementia and global morbidity–improved identification of presymptomatic high-risk individuals and identification of new circulating biomarkers are key public health needs. Here, we tested the hypothesis that a polygenic predictor of risk for Alzheimer’s dis...

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Detalles Bibliográficos
Autores principales: Paranjpe, Manish D., Chaffin, Mark, Zahid, Sohail, Ritchie, Scott, Rotter, Jerome I., Rich, Stephen S., Gerszten, Robert, Guo, Xiuqing, Heckbert, Susan, Tracy, Russ, Danesh, John, Lander, Eric S., Inouye, Michael, Kathiresan, Sekar, Butterworth, Adam S., Khera, Amit V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9436054/
https://www.ncbi.nlm.nih.gov/pubmed/36048760
http://dx.doi.org/10.1371/journal.pgen.1010294