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Histone deacetylase 6 plays an important role in TGF-β-induced murine Treg cell differentiation by regulating cell proliferation

Regulatory T (Treg) cells maintain immune homeostasis by preventing abnormal or excessive immune responses. Histone deacetylase 6 (HDAC6) regulates expression of Foxp3, and thus, Treg cell differentiation; however, its role in Treg cell differentiation is unclear and somewhat controversial. Here, we...

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Detalles Bibliográficos
Autores principales: Lee, Ji Hyeon, Kim, Hyeong Su, Jang, Sung Woong, Lee, Gap Ryol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9800578/
https://www.ncbi.nlm.nih.gov/pubmed/36581745
http://dx.doi.org/10.1038/s41598-022-27230-7