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Analysis of Wild Type and Variant B Cystatin C Interactome in Retinal Pigment Epithelium Cells Reveals Variant B Interacting Mitochondrial Proteins

Cystatin C, a secreted cysteine protease inhibitor, is abundantly expressed in retinal pigment epithelium (RPE) cells. A mutation in the protein’s leader sequence, corresponding to formation of an alternate variant B protein, has been linked with an increased risk for both age-related macular degene...

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Detalles Bibliográficos
Autores principales: Carlsson, Emil, Sharif, Umar, Supharattanasitthi, Wasu, Paraoan, Luminita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10001352/
https://www.ncbi.nlm.nih.gov/pubmed/36899848
http://dx.doi.org/10.3390/cells12050713