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Replication‐induced DNA secondary structures drive fork uncoupling and breakage

Sequences that form DNA secondary structures, such as G‐quadruplexes (G4s) and intercalated‐Motifs (iMs), are abundant in the human genome and play various physiological roles. However, they can also interfere with replication and threaten genome stability. Multiple lines of evidence suggest G4s inh...

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Detalles Bibliográficos
Autores principales: Williams, Sophie L, Casas‐Delucchi, Corella S, Raguseo, Federica, Guneri, Dilek, Li, Yunxuan, Minamino, Masashi, Fletcher, Emma E, Yeeles, Joseph TP, Keyser, Ulrich F, Waller, Zoë AE, Di Antonio, Marco, Coster, Gideon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10646557/
https://www.ncbi.nlm.nih.gov/pubmed/37781931
http://dx.doi.org/10.15252/embj.2023114334