DIDS, a chemical compound that inhibits RAD51-mediated homologous pairing and strand exchange
RAD51, an essential eukaryotic DNA recombinase, promotes homologous pairing and strand exchange during homologous recombination and the recombinational repair of double strand breaks. Mutations that up- or down-regulate RAD51 gene expression have been identified in several tumors, suggesting that in...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691838/ https://www.ncbi.nlm.nih.gov/pubmed/19336413 http://dx.doi.org/10.1093/nar/gkp200 |