DIDS, a chemical compound that inhibits RAD51-mediated homologous pairing and strand exchange

RAD51, an essential eukaryotic DNA recombinase, promotes homologous pairing and strand exchange during homologous recombination and the recombinational repair of double strand breaks. Mutations that up- or down-regulate RAD51 gene expression have been identified in several tumors, suggesting that in...

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Detalles Bibliográficos
Autores principales: Ishida, Takako, Takizawa, Yoshimasa, Kainuma, Takashi, Inoue, Jin, Mikawa, Tsutomu, Shibata, Takehiko, Suzuki, Hidekazu, Tashiro, Satoshi, Kurumizaka, Hitoshi
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691838/
https://www.ncbi.nlm.nih.gov/pubmed/19336413
http://dx.doi.org/10.1093/nar/gkp200