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Human Neurospheres as Three-Dimensional Cellular Systems for Developmental Neurotoxicity Testing
BACKGROUND: Developmental neurotoxicity (DNT) of environmental chemicals is a serious threat to human health. Current DNT testing guidelines propose investigations in rodents, which require large numbers of animals. With regard to the “3 Rs” (reduction, replacement, and refinement) of animal testing...
Autores principales: | Moors, Michaela, Rockel, Thomas Dino, Abel, Josef, Cline, Jason E., Gassmann, Kathrin, Schreiber, Timm, Schuwald, Janette, Weinmann, Nicole, Fritsche, Ellen |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
National Institute of Environmental Health Sciences
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2717141/ https://www.ncbi.nlm.nih.gov/pubmed/19654924 http://dx.doi.org/10.1289/ehp.0800207 |
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