Ubiquitination is involved in secondary growth, not initial formation of polyglutamine protein aggregates in C. elegans

BACKGROUND: Protein misfolding and subsequent aggregation are hallmarks of several human diseases. The cell has a variety of mechanisms for coping with misfolded protein stress, including ubiquitin-mediated protein degradation. In fact, the presence of ubiquitin at protein aggregates is a common fea...

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Detalles Bibliográficos
Autores principales: Skibinski, Gregory A, Boyd, Lynn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368771/
https://www.ncbi.nlm.nih.gov/pubmed/22494772
http://dx.doi.org/10.1186/1471-2121-13-10

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3368771/
https://www.ncbi.nlm.nih.gov/pubmed/22494772
http://dx.doi.org/10.1186/1471-2121-13-10

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