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Paraquat Poisoning Induces TNF-α-Dependent iNOS/NO Mediated Hyporesponsiveness of the Aorta to Vasoconstrictors in Rats
Paraquat is a toxic herbicide that may induce acute lung injury, circulatory failure and death. The present work aimed at investigating whether there is systemic inflammation and vascular dysfunction after paraquat exposure and whether these parameters were related. There was neutrophilia and accumu...
Autores principales: | Aires, Rosária D., Capettini, Luciano S. A., Silva, Josiane F., Rodrigues-Machado, Maria da Glória, Pinho, Vanessa, Teixeira, Mauro M., Cortes, Steyner F., Lemos, Virginia S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767802/ https://www.ncbi.nlm.nih.gov/pubmed/24039983 http://dx.doi.org/10.1371/journal.pone.0073562 |
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