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NMK-TD-100, a Novel Microtubule Modulating Agent, Blocks Mitosis and Induces Apoptosis in HeLa Cells by Binding to Tubulin
Thiadiazoles are one of the most widely utilized agents in medicinal chemistry, having a wide range of pharmacologic activity. Microtubules (MTs) have always remained a sought-after target in rapidly proliferating cancer cells. We screened for the growth inhibitory effect of synthetic 5-(3-indolyl)-...
Autores principales: | Bhattacharya, Surela, Kumar, N. Maruthi, Ganguli, Arnab, Tantak, Mukund P., Kumar, Dalip, Chakrabarti, Gopal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792137/ https://www.ncbi.nlm.nih.gov/pubmed/24116100 http://dx.doi.org/10.1371/journal.pone.0076286 |
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