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Massively parallel read mapping on GPUs with the q-group index and PEANUT
We present the q-group index, a novel data structure for read mapping tailored towards graphics processing units (GPUs) with a small memory footprint and efficient parallel algorithms for querying and building. On top of the q-group index we introduce PEANUT, a highly parallel GPU-based read mapper....
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
PeerJ Inc.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184027/ https://www.ncbi.nlm.nih.gov/pubmed/25289191 http://dx.doi.org/10.7717/peerj.606 |
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author | Köster, Johannes Rahmann, Sven |
author_facet | Köster, Johannes Rahmann, Sven |
author_sort | Köster, Johannes |
collection | PubMed |
description | We present the q-group index, a novel data structure for read mapping tailored towards graphics processing units (GPUs) with a small memory footprint and efficient parallel algorithms for querying and building. On top of the q-group index we introduce PEANUT, a highly parallel GPU-based read mapper. PEANUT provides the possibility to output both the best hits or all hits of a read. Our benchmarks show that PEANUT outperforms other state-of-the-art read mappers in terms of speed while maintaining or slightly increasing precision, recall and sensitivity. |
format | Online Article Text |
id | pubmed-4184027 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | PeerJ Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-41840272014-10-06 Massively parallel read mapping on GPUs with the q-group index and PEANUT Köster, Johannes Rahmann, Sven PeerJ Bioinformatics We present the q-group index, a novel data structure for read mapping tailored towards graphics processing units (GPUs) with a small memory footprint and efficient parallel algorithms for querying and building. On top of the q-group index we introduce PEANUT, a highly parallel GPU-based read mapper. PEANUT provides the possibility to output both the best hits or all hits of a read. Our benchmarks show that PEANUT outperforms other state-of-the-art read mappers in terms of speed while maintaining or slightly increasing precision, recall and sensitivity. PeerJ Inc. 2014-09-30 /pmc/articles/PMC4184027/ /pubmed/25289191 http://dx.doi.org/10.7717/peerj.606 Text en © 2014 Köster and Rahmann http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited. |
spellingShingle | Bioinformatics Köster, Johannes Rahmann, Sven Massively parallel read mapping on GPUs with the q-group index and PEANUT |
title | Massively parallel read mapping on GPUs with the q-group index and PEANUT |
title_full | Massively parallel read mapping on GPUs with the q-group index and PEANUT |
title_fullStr | Massively parallel read mapping on GPUs with the q-group index and PEANUT |
title_full_unstemmed | Massively parallel read mapping on GPUs with the q-group index and PEANUT |
title_short | Massively parallel read mapping on GPUs with the q-group index and PEANUT |
title_sort | massively parallel read mapping on gpus with the q-group index and peanut |
topic | Bioinformatics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184027/ https://www.ncbi.nlm.nih.gov/pubmed/25289191 http://dx.doi.org/10.7717/peerj.606 |
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