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Massively parallel read mapping on GPUs with the q-group index and PEANUT

We present the q-group index, a novel data structure for read mapping tailored towards graphics processing units (GPUs) with a small memory footprint and efficient parallel algorithms for querying and building. On top of the q-group index we introduce PEANUT, a highly parallel GPU-based read mapper....

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Detalles Bibliográficos
Autores principales: Köster, Johannes, Rahmann, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184027/
https://www.ncbi.nlm.nih.gov/pubmed/25289191
http://dx.doi.org/10.7717/peerj.606
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author Köster, Johannes
Rahmann, Sven
author_facet Köster, Johannes
Rahmann, Sven
author_sort Köster, Johannes
collection PubMed
description We present the q-group index, a novel data structure for read mapping tailored towards graphics processing units (GPUs) with a small memory footprint and efficient parallel algorithms for querying and building. On top of the q-group index we introduce PEANUT, a highly parallel GPU-based read mapper. PEANUT provides the possibility to output both the best hits or all hits of a read. Our benchmarks show that PEANUT outperforms other state-of-the-art read mappers in terms of speed while maintaining or slightly increasing precision, recall and sensitivity.
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spelling pubmed-41840272014-10-06 Massively parallel read mapping on GPUs with the q-group index and PEANUT Köster, Johannes Rahmann, Sven PeerJ Bioinformatics We present the q-group index, a novel data structure for read mapping tailored towards graphics processing units (GPUs) with a small memory footprint and efficient parallel algorithms for querying and building. On top of the q-group index we introduce PEANUT, a highly parallel GPU-based read mapper. PEANUT provides the possibility to output both the best hits or all hits of a read. Our benchmarks show that PEANUT outperforms other state-of-the-art read mappers in terms of speed while maintaining or slightly increasing precision, recall and sensitivity. PeerJ Inc. 2014-09-30 /pmc/articles/PMC4184027/ /pubmed/25289191 http://dx.doi.org/10.7717/peerj.606 Text en © 2014 Köster and Rahmann http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose provided that it is properly attributed. For attribution, the original author(s), title, publication source (PeerJ) and either DOI or URL of the article must be cited.
spellingShingle Bioinformatics
Köster, Johannes
Rahmann, Sven
Massively parallel read mapping on GPUs with the q-group index and PEANUT
title Massively parallel read mapping on GPUs with the q-group index and PEANUT
title_full Massively parallel read mapping on GPUs with the q-group index and PEANUT
title_fullStr Massively parallel read mapping on GPUs with the q-group index and PEANUT
title_full_unstemmed Massively parallel read mapping on GPUs with the q-group index and PEANUT
title_short Massively parallel read mapping on GPUs with the q-group index and PEANUT
title_sort massively parallel read mapping on gpus with the q-group index and peanut
topic Bioinformatics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184027/
https://www.ncbi.nlm.nih.gov/pubmed/25289191
http://dx.doi.org/10.7717/peerj.606
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