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Identification of a gene regulatory network associated with prion replication

Prions consist of aggregates of abnormal conformers of the cellular prion protein (PrP(C)). They propagate by recruiting host-encoded PrP(C) although the critical interacting proteins and the reasons for the differences in susceptibility of distinct cell lines and populations are unknown. We derived...

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Detalles Bibliográficos
Autores principales: Marbiah, Masue M, Harvey, Anna, West, Billy T, Louzolo, Anais, Banerjee, Priya, Alden, Jack, Grigoriadis, Anita, Hummerich, Holger, Kan, Ho-Man, Cai, Ying, Bloom, George S, Jat, Parmjit, Collinge, John, Klöhn, Peter-Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4198050/
https://www.ncbi.nlm.nih.gov/pubmed/24843046
http://dx.doi.org/10.15252/embj.201387150