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Superresolution Modeling of Calcium Release in the Heart
Stable calcium-induced calcium release (CICR) is critical for maintaining normal cellular contraction during cardiac excitation-contraction coupling. The fundamental element of CICR in the heart is the calcium (Ca(2+)) spark, which arises from a cluster of ryanodine receptors (RyR). Opening of these...
Autores principales: | Walker, Mark A., Williams, George S.B., Kohl, Tobias, Lehnart, Stephan E., Jafri, M. Saleet, Greenstein, Joseph L., Lederer, W.J., Winslow, Raimond L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269784/ https://www.ncbi.nlm.nih.gov/pubmed/25517166 http://dx.doi.org/10.1016/j.bpj.2014.11.003 |
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