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Cardiomyocyte Ca(2+) handling and structure is regulated by degree and duration of mechanical load variation
Cardiac transverse (t)-tubules are altered during disease and may be regulated by stretch-sensitive molecules. The relationship between variations in the degree and duration of load and t-tubule structure remains unknown, as well as its implications for local Ca(2+)-induced Ca(2+) release (CICR). Ra...
Autores principales: | Ibrahim, Michael, Kukadia, Punam, Siedlecka, Urszula, Cartledge, James E, Navaratnarajah, Manoraj, Tokar, Sergiy, Van Doorn, Carin, Tsang, Victor T, Gorelik, Julia, Yacoub, Magdi H, Terracciano, Cesare M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393719/ https://www.ncbi.nlm.nih.gov/pubmed/22862818 http://dx.doi.org/10.1111/j.1582-4934.2012.01611.x |
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