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Role of the splicing factor SRSF4 in cisplatin-induced modifications of pre-mRNA splicing and apoptosis

BACKGROUND: Modification of splicing by chemotherapeutic drugs has usually been evaluated on a limited number of pre-mRNAs selected for their recognized or potential importance in cell proliferation or apoptosis. However, the pathways linking splicing alterations to the efficiency of cancer therapy...

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Detalles Bibliográficos
Autores principales: Gabriel, Maude, Delforge, Yves, Deward, Adeline, Habraken, Yvette, Hennuy, Benoit, Piette, Jacques, Klinck, Roscoe, Chabot, Benoit, Colige, Alain, Lambert, Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4399393/
https://www.ncbi.nlm.nih.gov/pubmed/25884497
http://dx.doi.org/10.1186/s12885-015-1259-0