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SomInaClust: detection of cancer genes based on somatic mutation patterns of inactivation and clustering
BACKGROUND: With the advances in high throughput technologies, increasing amounts of cancer somatic mutation data are being generated and made available. Only a small number of (driver) mutations occur in driver genes and are responsible for carcinogenesis, while the majority of (passenger) mutation...
Autores principales: | Van den Eynden, Jimmy, Fierro, Ana Carolina, Verbeke, Lieven PC, Marchal, Kathleen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4410004/ https://www.ncbi.nlm.nih.gov/pubmed/25903787 http://dx.doi.org/10.1186/s12859-015-0555-7 |
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