MALT1 Protease Activity Is Required for Innate and Adaptive Immune Responses

CARMA-BCL10-MALT1 signalosomes play important roles in antigen receptor signaling and other pathways. Previous studies have suggested that as part of this complex, MALT1 functions as both a scaffolding protein to activate NF-κB through recruitment of ubiquitin ligases, and as a protease to cleave an...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Jong W., Hoffman, Sandy, Beal, Allison M., Dykon, Angela, Ringenberg, Michael A., Hughes, Anna C., Dare, Lauren, Anderson, Amber D., Finger, Joshua, Kasparcova, Viera, Rickard, David, Berger, Scott B., Ramanjulu, Joshi, Emery, John G., Gough, Peter J., Bertin, John, Foley, Kevin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428694/
https://www.ncbi.nlm.nih.gov/pubmed/25965667
http://dx.doi.org/10.1371/journal.pone.0127083

Ejemplares similares

Ejemplares similares