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Age-Dependent Defects of Regulatory B Cells in Wiskott-Aldrich Syndrome Gene Knockout Mice
The Wiskott-Aldrich syndrome (WAS) is a rare X-linked primary immunodeficiency characterized by recurrent infections, thrombocytopenia, eczema, and high incidence of malignancy and autoimmunity. The cellular mechanisms underlying autoimmune complications in WAS have been extensively studied; however...
Autores principales: | Yokoyama, Tadafumi, Yoshizaki, Ayumi, Simon, Karen L., Kirby, Martha R., Anderson, Stacie M., Candotti, Fabio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4598155/ https://www.ncbi.nlm.nih.gov/pubmed/26448644 http://dx.doi.org/10.1371/journal.pone.0139729 |
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