Cargando…

Influenza Vaccine Manufacturing: Effect of Inactivation, Splitting and Site of Manufacturing. Comparison of Influenza Vaccine Production Processes

The aim of this study was to evaluate the impact of different inactivation and splitting procedures on influenza vaccine product composition, stability and recovery to support transfer of process technology. Four split and two whole inactivated virus (WIV) influenza vaccine bulks were produced and c...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kon, Theone C., Onu, Adrian, Berbecila, Laurentiu, Lupulescu, Emilia, Ghiorgisor, Alina, Kersten, Gideon F., Cui, Yi-Qing, Amorij, Jean-Pierre, Van der Pol, Leo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4784929/ https://www.ncbi.nlm.nih.gov/pubmed/26959983 http://dx.doi.org/10.1371/journal.pone.0150700

Ejemplares similares

Development of Cross-Protective Influenza A Vaccines Based on Cellular Responses
por: Soema, Peter Christiaan, et al.
Publicado: (2015)

Development of Thermostable Lyophilized Inactivated Polio Vaccine
por: Kraan, Heleen, et al.
Publicado: (2014)

Influenza T-cell Epitope-Loaded Virosomes Adjuvanted with CpG as a Potential Influenza Vaccine
por: Soema, Peter C., et al.
Publicado: (2014)

Current and Emerging Cell Culture Manufacturing Technologies for Influenza Vaccines
por: Milián, Ernest, et al.
Publicado: (2015)

Influenza vaccines: the potential benefits of cell-culture isolation and manufacturing
por: Rajaram, Sankarasubramanian, et al.
Publicado: (2020)

Surveillance of Vaccination Coverage of Inactivated Influenza Vaccines and Allergic Rash Adverse Events Following Immunization for Children From 6 Manufacturers
por: Li, Zhi-qun, et al.
Publicado: (2023)

Evaluation of determinants of the serological response to the quadrivalent split‐inactivated influenza vaccine
por: Wu, Shaohuan, et al.
Publicado: (2022)

Incompatibility of lyophilized inactivated polio vaccine with liquid pentavalent whole-cell-pertussis-containing vaccine
por: Kraan, Heleen, et al.
Publicado: (2016)

Influenza viruses circulation and the effectiveness of seasonal influenza vaccine in Romania during the season 2013-2014
por: Pițigoi, Daniela, et al.
Publicado: (2014)

Next Generation Inactivated Polio Vaccine Manufacturing to Support Post Polio-Eradication Biosafety Goals
por: Thomassen, Yvonne E., et al.
Publicado: (2013)

The manufacturing process should remain the focus for severe febrile reactions in children administered an Australian inactivated influenza vaccine during 2010
por: Li‐Kim‐Moy, Jean, et al.
Publicado: (2015)

Whole-Inactivated Influenza Virus Is a Potent Adjuvant for Influenza Peptides Containing CD8(+) T Cell Epitopes
por: Soema, Peter C., et al.
Publicado: (2018)

Immunogenicity of Split Inactivated Quadrivalent Influenza Vaccine in Adults with Obesity in the 2017/2018 Season
por: Jagielska, Anna M., et al.
Publicado: (2021)

Vaccine manufacturing
por: Gomez, Phillip L., et al.
Publicado: (2013)

Vaccine Manufacturing
por: Gomez, Phillip L., et al.
Publicado: (2018)

Influenza Vaccination Strategies: Comparing Inactivated and Live Attenuated Influenza Vaccines
por: Sridhar, Saranya, et al.
Publicado: (2015)

A historically-controlled Phase III study in adults to characterize the acceptability of a process change for manufacturing inactivated quadrivalent influenza vaccine
por: Jain, Varsha K, et al.
Publicado: (2014)

Performance characteristics of qualified cell lines for isolation and propagation of influenza viruses for vaccine manufacturing
por: Donis, Ruben O., et al.
Publicado: (2014)

A Promising IFN-Deficient System to Manufacture IFN-Sensitive Influenza Vaccine Virus
por: Chen, Can, et al.
Publicado: (2018)

2743. Safety of Recombinant Influenza Vaccine Compared with Inactivated Influenza Vaccine in Adults
por: Hansen, John, et al.
Publicado: (2019)

Bioprocess development for universal influenza vaccines based on inactivated split chimeric and mosaic hemagglutinin viruses
por: Puente-Massaguer, Eduard, et al.
Publicado: (2023)

Solid Bioneedle-Delivered Influenza Vaccines Are Highly Thermostable and Induce Both Humoral and Cellular Immune Responses
por: Soema, Peter C., et al.
Publicado: (2014)

Impact of age and pre-existing influenza immune responses in humans receiving split inactivated influenza vaccine on the induction of the breadth of antibodies to influenza A strains
por: Nuñez, Ivette A., et al.
Publicado: (2017)

A vaccine manufacturer’s approach to address medical needs related to seasonal and pandemic influenza viruses
por: Baras, Benoit, et al.
Publicado: (2008)

Cell-Based Manufacturing Technology Increases Antigenic Match of Influenza Vaccine and Results in Improved Effectiveness
por: Rockman, Steven, et al.
Publicado: (2022)

Safety of Recombinant Influenza Vaccine Compared to Inactivated Influenza Vaccine in Adults: An Observational Study
por: Hansen, John, et al.
Publicado: (2020)

Enhanced passive safety surveillance of a quadrivalent inactivated split virion influenza vaccine in Finland during the influenza season 2020/21
por: Syrkina, Olga, et al.
Publicado: (2022)

Safety and tolerability of a 2009 trivalent inactivated split‐virion influenza vaccine in infants, children and adolescents
por: Lambert, Stephen B., et al.
Publicado: (2013)

Assessment of an optimized manufacturing process for inactivated quadrivalent influenza vaccine: a phase III, randomized, double-blind, safety and immunogenicity study in children and adults
por: Claeys, Carine, et al.
Publicado: (2018)

Development of Stable Influenza Vaccine Powder Formulations: Challenges and Possibilities
por: Amorij, J-P., et al.
Publicado: (2008)

Enhanced passive safety surveillance of the quadrivalent inactivated split-virion influenza vaccine (IIV4) in Finland during the 2019/20 influenza season
por: Chabanon, Anne-Laure, et al.
Publicado: (2021)

1059 Expanded immunogenicity of high-dose inactivated influenza vaccine compared to standard-dose inactivated influenza vaccine in older adults
por: Diazgranados, Carlos, et al.
Publicado: (2014)

Preservation of the Immunogenicity of Dry-powder Influenza H5N1 Whole Inactivated Virus Vaccine at Elevated Storage Temperatures
por: Geeraedts, Felix, et al.
Publicado: (2010)

Immunogenicity and safety of an intramuscular split-virion quadrivalent inactivated influenza vaccine in individuals aged ≥ 6 months in India
por: Agarkhedkar, Sharad, et al.
Publicado: (2019)

Assessing the Importance of Domestic Vaccine Manufacturing Centers: An Overview of Immunization Programs, Vaccine Manufacture, and Distribution
por: Rey-Jurado, Emma, et al.
Publicado: (2018)

Immunogenicity and safety of an inactivated enterovirus 71 vaccine coadministered with trivalent split-virion inactivated influenza vaccine: A phase 4, multicenter, randomized, controlled trial in China
por: Chen, Yaping, et al.
Publicado: (2022)

Buccal and sublingual vaccine delivery
por: Kraan, Heleen, et al.
Publicado: (2014)

Standardisation of inactivated influenza vaccines—Learning from history
por: Wood, John M., et al.
Publicado: (2018)

An Improved Inactivated Influenza Vaccine with Enhanced Cross Protection
por: Ni, Yawei, et al.
Publicado: (2018)

Update of inactivated equine influenza vaccine strain in Japan
por: GAMOH, Koichiro, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_38q6p6aa84rrg0v1gv1gp2otk1