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Bullatine A stimulates spinal microglial dynorphin A expression to produce anti-hypersensitivity in a variety of rat pain models

BACKGROUND: Aconiti brachypodi Radix (Xue-shang-yi-zhi-hao) has been prescribed to manage chronic pain, arthritis, and traumatic injuries. Bullatine A, a C(20)-diterpenoid alkaloid, is one of its principle effective compounds. This study aimed to investigate the anti-hypersensitivity of bullatine A...

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Detalles Bibliográficos
Autores principales:	Huang, Qian, Mao, Xiao-Fang, Wu, Hai-Yun, Li, Teng-Fei, Sun, Ming-Li, Liu, Hao, Wang, Yong-Xiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5006272/ https://www.ncbi.nlm.nih.gov/pubmed/27577933 http://dx.doi.org/10.1186/s12974-016-0696-2

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